PFO Closure Device Market Research Report from 2023 forecast to 2029, by Manufacturers, Regions, Type and Application

The global PFO Closure Device market size was valued at USD 124.9 million in 2022 and is forecast to a readjusted size of USD 208.1 million by 2029 with a CAGR of 7.6% during review period.

Patent Foramen Ovale (PFO), A hole in your heart would seem to be the very definition of a “problem.” Yet more than a quarter of the population has one, and for most it causes no adverse health effects. In fact, the vast majority of those affected don’t even know it.

There are two kinds of holes in the heart. One is called an atrial septal defect (ASD), and the other is a patent foramen ovale (PFO). Although both are holes in the wall of tissue (septum) between the left and right upper chambers of the heart (atria), their causes are quite different. An ASD is a failure of the septal tissue to form between the atria, and as such it is considered a congenital heart defect, something that you are born with. Generally, an ASD hole is larger than that of a PFO. The larger the hole, the more likely there are to be symptoms.

The main market for PFO shut-off devices is Europe with approximately 55%, followed by North America with approximately 20%. Abbott, Occlutech and Starway are the leading manufacturers, with Abbott leading the world with about 70%. Non-degradable PFO Occluder is the main type, with a share about 93%.

This report is a detailed and comprehensive analysis for global PFO Closure Device market. Both quantitative and qualitative analyses are presented by manufacturers, by region & country, by Type and by Application. As the market is constantly changing, this report explores the competition, supply and demand trends, as well as key factors that contribute to its changing demands across many markets. Company profiles and product examples of selected competitors, along with market share estimates of some of the selected leaders for the year 2023, are provided.

Key Features:

Global PFO Closure Device market size and forecasts, in consumption value ($ Million), sales quantity (Units), and average selling prices (US$/Unit), 2018-2029
Global PFO Closure Device market size and forecasts by region and country, in consumption value ($ Million), sales quantity (Units), and average selling prices (US$/Unit), 2018-2029
Global PFO Closure Device market size and forecasts, by Type and by Application, in consumption value ($ Million), sales quantity (Units), and average selling prices (US$/Unit), 2018-2029
Global PFO Closure Device market shares of main players, shipments in revenue ($ Million), sales quantity (Units), and ASP (US$/Unit), 2018-2023

The Primary Objectives in This Report Are:

To determine the size of the total market opportunity of global and key countries
To assess the growth potential for PFO Closure Device
To forecast future growth in each product and end-use market
To assess competitive factors affecting the marketplace

This report profiles key players in the global PFO Closure Device market based on the following parameters - company overview, production, value, price, gross margin, product portfolio, geographical presence, and key developments.

This report also provides key insights about market drivers, restraints, opportunities, new product launches or approvals, COVID-19 and Russia-Ukraine War Influence.

   Abbott
   Occlutech
   Starway
   W. L. Gore & Associates
   Cardia
   LifeTech

   Non-degradable
   Degradable

   Public Hospital
   Private Hospital

   North America (United States, Canada and Mexico)
   Europe (Germany, France, United Kingdom, Russia, Italy, and Rest of Europe)
   Asia-Pacific (China, Japan, Korea, India, Southeast Asia, and Australia)
   South America (Brazil, Argentina, Colombia, and Rest of South America)
   Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa, and Rest of Middle East & Africa)

What are the strengths of the PFO Closure Device Market in 2025?

The PFO closure device market is expected to grow due to the increasing prevalence of patent foramen ovale (PFO)-related health conditions such as strokes and migraines. Advancements in device technology, such as better safety profiles and ease of use, also contribute to growth. Additionally, regulatory approvals for new, more effective devices will likely enhance market demand.

What weaknesses could hinder the market's growth in 2025?

One of the key weaknesses is the high cost of PFO closure procedures, which may limit access in lower-income regions. Additionally, the need for long-term follow-up care could deter some patients and healthcare providers. Limited awareness about PFO among the general public might also slow adoption.

What opportunities exist for the PFO Closure Device Market in 2025?

Emerging markets, particularly in Asia-Pacific and Latin America, present significant opportunities for expansion, as awareness and treatment options for PFO improve. There is also an opportunity for companies to develop devices with enhanced features like minimally invasive procedures, which would increase patient preference and hospital adoption.

What threats could affect the PFO Closure Device Market in 2025?

The market faces threats from competitive alternatives such as medical therapies, which can be used to treat PFO-related conditions without the need for surgery. Additionally, the introduction of new regulatory policies or reimbursement challenges could hinder market growth. Rising competition from companies developing similar devices could also reduce profit margins.

What political factors could impact the PFO Closure Device Market in 2025?

Government healthcare policies and reimbursement frameworks will play a crucial role. Countries with favorable policies for medical device approvals and reimbursement can stimulate market growth, while those with stringent regulations or budget cuts in healthcare may slow down the adoption of PFO closure devices.

How could the economic environment influence the PFO Closure Device Market?

Economic conditions affect the affordability of PFO closure procedures, especially in regions where healthcare access is limited. During economic downturns, hospitals may reduce spending on expensive medical devices, impacting market growth. However, in high-income regions, rising healthcare expenditure could increase demand for advanced treatment options like PFO closure devices.

What social factors are relevant to the PFO Closure Device Market in 2025?

An increasing awareness of PFO-related health risks such as strokes and migraines is likely to raise patient demand for closure devices. However, cultural differences in the acceptance of surgical interventions may impact the speed of adoption in certain regions. Patient advocacy and education campaigns could further drive awareness and market expansion.

What technological advancements could influence the PFO Closure Device Market?

Technological improvements in device design, such as minimally invasive techniques and enhanced safety features, will be key to market growth. Additionally, advancements in imaging and diagnostic tools will improve the identification of PFOs, leading to earlier interventions and a greater demand for closure devices.

What environmental factors should be considered for the PFO Closure Device Market?

Environmental sustainability is becoming increasingly important in medical device manufacturing. Companies that adopt eco-friendly production methods or develop biodegradable components may attract positive attention. However, the environmental impact of medical waste associated with these devices needs to be addressed to align with global sustainability goals.

What legal factors could affect the PFO Closure Device Market in 2025?

Changes in medical device regulations, including stricter safety and efficacy testing requirements, could delay market entry for new PFO closure devices. Intellectual property rights, patent disputes, and product liability risks also represent potential challenges. Ensuring compliance with international standards will be crucial for manufacturers looking to expand into multiple regions.

Who are the suppliers in the PFO Closure Device Market?

Suppliers include manufacturers of medical devices, raw material suppliers (such as metals, polymers, and biocompatible materials), and technology providers for imaging systems used in PFO diagnosis. Additionally, regulatory bodies that ensure compliance with safety standards play a crucial role in the supply chain.

What are the inputs required for the PFO Closure Device Market?

Inputs include advanced research and development for device design, regulatory approvals, high-quality raw materials for device construction, and skilled labor for manufacturing. Additionally, diagnostic tools and procedures to detect PFOs, along with clinical trial data, are essential to validate the device's effectiveness and safety.

What are the processes involved in the PFO Closure Device Market?

Processes include product development and design, clinical trials to assess efficacy and safety, regulatory approval processes, manufacturing, and distribution to hospitals or clinics. Post-market surveillance and continuous improvements based on patient feedback and data are also key parts of the process.

Who are the customers in the PFO Closure Device Market?

Customers include hospitals, cardiology clinics, and healthcare providers specializing in heart and vascular treatments. Patients diagnosed with PFO-related conditions, especially those who suffer from strokes or migraines, are the end consumers of the device. Insurance companies also play a role in reimbursement decisions.

What are the expected outputs of the PFO Closure Device Market?

The expected outputs are successfully developed and marketed PFO closure devices, clinical data demonstrating safety and efficacy, and increased patient outcomes through reduced complications related to PFO. Additionally, revenue from device sales, market expansion into new regions, and positive patient feedback are key outputs.

What is the threat of new entrants in the PFO Closure Device Market?

The threat of new entrants is moderate. While the market holds potential for growth, high barriers to entry such as strict regulatory requirements, large capital investment, and the need for specialized knowledge limit the number of new players. Established companies with strong brands and technological expertise dominate the market, making it difficult for newcomers to compete effectively.

How strong is the bargaining power of suppliers in the PFO Closure Device Market?

The bargaining power of suppliers is relatively low. The supply chain for PFO closure devices relies on specialized raw materials like biocompatible metals and polymers, but these materials are widely available. Additionally, many manufacturers can source materials from multiple suppliers, reducing their dependence on any single supplier.

How strong is the bargaining power of buyers in the PFO Closure Device Market?

The bargaining power of buyers is moderate. While hospitals and healthcare providers are the primary buyers, they face limited options for PFO closure devices, especially with established brands dominating the market. However, as more companies develop new technologies and devices, buyers may gain leverage in negotiating prices and terms.

What is the threat of substitute products in the PFO Closure Device Market?

The threat of substitutes is moderate to high. Non-surgical treatments, including anticoagulants and antiplatelet therapies, provide alternative options for managing PFO-related health risks like stroke. As these medical therapies continue to evolve, they could pose competition to the market for closure devices, especially in patients who prefer less invasive solutions.

How intense is the competitive rivalry in the PFO Closure Device Market?

The competitive rivalry is high. Major players in the market, including large medical device companies, are constantly innovating and improving their products to maintain market share. New technologies and advancements in minimally invasive techniques increase competition, while price pressures from healthcare systems and insurers further intensify rivalry among existing players.

What are the key upstream factors influencing the PFO Closure Device Market?

Upstream factors include the availability and cost of raw materials required for device production, such as biocompatible metals, polymers, and medical-grade adhesives. Additionally, technological advancements in manufacturing processes and the availability of skilled labor play a significant role in the production of high-quality devices. The research and development investments made by companies to improve device safety and efficacy are also critical upstream factors.

How does the regulatory environment impact the upstream components of the PFO Closure Device Market?

The regulatory environment has a strong impact on upstream components. Medical device manufacturers must adhere to stringent regulatory guidelines for safety, efficacy, and quality control. The need for clinical trials, FDA approvals, and international certifications can delay production and increase costs. Any changes in regulations or delays in approvals can directly affect the timelines for manufacturing and distribution.

What role does the supply chain play in the upstream dynamics of the PFO Closure Device Market?

The supply chain plays a pivotal role, particularly in the procurement of specialized materials and components used in device production. Disruptions in the supply of raw materials, such as delays from key suppliers or fluctuations in material costs, can affect the production schedule and overall pricing. Additionally, efficient logistics and strong relationships with suppliers are essential for maintaining consistent quality and timely delivery.

How do research and development investments affect the upstream analysis of the PFO Closure Device Market?

R&D investments are crucial for the upstream dynamics of the market. Ongoing innovation in device technology, such as developing minimally invasive options or improving the closure mechanism, requires significant research resources. These investments drive the creation of new devices and help companies stay competitive. However, high R&D costs can affect the pricing strategy and production timelines.

What external factors could impact the upstream components of the PFO Closure Device Market?

External factors such as geopolitical events, economic shifts, and changes in trade policies can affect the upstream components. For instance, tariffs or trade restrictions on raw materials from key suppliers can disrupt production timelines or increase costs. Similarly, economic downturns can reduce investments in R&D or slow down procurement, impacting device availability.

What are the key midstream activities in the PFO Closure Device Market?

Midstream activities involve the manufacturing processes that convert raw materials into finished products, including device assembly, quality control, and testing. This phase also includes packaging, sterilization, and regulatory compliance checks before the products are ready for distribution. Ensuring consistency in device performance and adhering to industry standards are crucial in this stage.

How does distribution impact the midstream components of the PFO Closure Device Market?

Distribution plays a vital role in making PFO closure devices accessible to healthcare providers. Efficient logistics, storage, and transportation are essential for ensuring that devices reach hospitals, clinics, and medical centers in a timely manner. Strong relationships with distributors and the ability to scale operations globally are critical to meeting growing demand.

What is the role of partnerships in the midstream stage of the PFO Closure Device Market?

Partnerships with hospitals, cardiology networks, and healthcare providers are essential during the midstream phase. These partnerships can influence how quickly new devices are adopted by the medical community. Collaborations with key opinion leaders and medical experts can also help to validate the effectiveness of devices, driving broader market acceptance.

How do regulatory requirements affect midstream operations in the PFO Closure Device Market?

Regulatory requirements significantly impact midstream operations. The manufacturing process must comply with stringent standards set by regulatory bodies like the FDA, EMA, and other global health authorities. Regular audits, adherence to Good Manufacturing Practices (GMP), and meeting safety and quality benchmarks are mandatory to ensure market access and avoid costly recalls or delays.

How does competition influence the midstream phase of the PFO Closure Device Market?

Competition influences midstream operations by encouraging innovation and pushing manufacturers to improve efficiency in production. Companies may adopt lean manufacturing techniques to reduce costs or invest in advanced technologies to differentiate their devices. Competitive pressure also drives companies to streamline distribution channels and ensure faster delivery to healthcare providers.

What are the key downstream activities in the PFO Closure Device Market?

Downstream activities primarily include marketing, sales, and post-sales support. This involves educating healthcare providers about the benefits of PFO closure devices, ensuring proper training for medical professionals, and providing patient education. Additionally, the management of device performance post-implantation, including follow-up care and addressing potential complications, is a critical part of downstream operations.

How does patient awareness affect the downstream dynamics of the PFO Closure Device Market?

Patient awareness plays a significant role in the downstream phase. As patients become more informed about PFO-related health risks like stroke or migraines, they are more likely to seek treatment options, thereby driving demand for closure devices. Awareness campaigns, patient advocacy groups, and consultations with healthcare providers can increase adoption rates and influence treatment decisions.

What role does the healthcare provider play in the downstream phase of the PFO Closure Device Market?

Healthcare providers are pivotal in the downstream phase, as they are the primary decision-makers in recommending PFO closure procedures. The level of trust in the device, ease of use, and clinical outcomes are key factors that influence their prescribing behavior. Additionally, ongoing training and support for healthcare professionals ensure proper implementation and optimal patient outcomes.

How do reimbursement policies impact the downstream components of the PFO Closure Device Market?

Reimbursement policies significantly affect market dynamics by determining the affordability and accessibility of PFO closure devices for patients. Favorable reimbursement policies encourage widespread adoption, while restrictive policies can limit access to the procedure, especially in regions with less healthcare funding. Healthcare providers are more likely to recommend devices if reimbursement rates are favorable and consistent.

How does competition in the downstream market affect PFO Closure Device adoption?

Competition among manufacturers in the downstream market drives innovation and enhances device features, improving patient outcomes and satisfaction. Companies with more effective marketing strategies, strong relationships with healthcare providers, and superior post-sales support can gain a competitive edge. Additionally, competitive pricing can influence adoption, especially in cost-sensitive healthcare systems.

Chapter 1, to describe PFO Closure Device product scope, market overview, market estimation caveats and base year.
Chapter 2, to profile the top manufacturers of PFO Closure Device, with price, sales, revenue and global market share of PFO Closure Device from 2018 to 2023.
Chapter 3, the PFO Closure Device competitive situation, sales quantity, revenue and global market share of top manufacturers are analyzed emphatically by landscape contrast.
Chapter 4, the PFO Closure Device breakdown data are shown at the regional level, to show the sales quantity, consumption value and growth by regions, from 2018 to 2029.
Chapter 5 and 6, to segment the sales by Type and application, with sales market share and growth rate by type, application, from 2018 to 2029.
Chapter 7, 8, 9, 10 and 11, to break the sales data at the country level, with sales quantity, consumption value and market share for key countries in the world, from 2017 to 2022.and PFO Closure Device market forecast, by regions, type and application, with sales and revenue, from 2024 to 2029.
Chapter 12, market dynamics, drivers, restraints, trends, Porters Five Forces analysis, and Influence of COVID-19 and Russia-Ukraine War.
Chapter 13, the key raw materials and key suppliers, and industry chain of PFO Closure Device.
Chapter 14 and 15, to describe PFO Closure Device sales channel, distributors, customers, research findings and conclusion.

1 Market Overview

   1.1 Product Overview and Scope of PFO Closure Device
   1.2 Market Estimation Caveats and Base Year
   1.3 Market Analysis by Type
       1.3.1 Overview: Global PFO Closure Device Consumption Value by Type: 2018 Versus 2022 Versus 2029
       1.3.2 Non-degradable
       1.3.3 Degradable
   1.4 Market Analysis by Application
       1.4.1 Overview: Global PFO Closure Device Consumption Value by Application: 2018 Versus 2022 Versus 2029
       1.4.2 Public Hospital
       1.4.3 Private Hospital
   1.5 Global PFO Closure Device Market Size & Forecast
       1.5.1 Global PFO Closure Device Consumption Value (2018 & 2022 & 2029)
       1.5.2 Global PFO Closure Device Sales Quantity (2018-2029)
       1.5.3 Global PFO Closure Device Average Price (2018-2029)

2 Manufacturers Profiles

   2.1 Abbott
       2.1.1 Abbott Details
       2.1.2 Abbott Major Business
       2.1.3 Abbott PFO Closure Device Product and Services
       2.1.4 Abbott PFO Closure Device Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2018-2023)
       2.1.5 Abbott Recent Developments/Updates
   2.2 Occlutech
       2.2.1 Occlutech Details
       2.2.2 Occlutech Major Business
       2.2.3 Occlutech PFO Closure Device Product and Services
       2.2.4 Occlutech PFO Closure Device Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2018-2023)
       2.2.5 Occlutech Recent Developments/Updates
   2.3 Starway
       2.3.1 Starway Details
       2.3.2 Starway Major Business
       2.3.3 Starway PFO Closure Device Product and Services
       2.3.4 Starway PFO Closure Device Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2018-2023)
       2.3.5 Starway Recent Developments/Updates
   2.4 W. L. Gore & Associates
       2.4.1 W. L. Gore & Associates Details
       2.4.2 W. L. Gore & Associates Major Business
       2.4.3 W. L. Gore & Associates PFO Closure Device Product and Services
       2.4.4 W. L. Gore & Associates PFO Closure Device Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2018-2023)
       2.4.5 W. L. Gore & Associates Recent Developments/Updates
   2.5 Cardia
       2.5.1 Cardia Details
       2.5.2 Cardia Major Business
       2.5.3 Cardia PFO Closure Device Product and Services
       2.5.4 Cardia PFO Closure Device Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2018-2023)
       2.5.5 Cardia Recent Developments/Updates
   2.6 LifeTech
       2.6.1 LifeTech Details
       2.6.2 LifeTech Major Business
       2.6.3 LifeTech PFO Closure Device Product and Services
       2.6.4 LifeTech PFO Closure Device Sales Quantity, Average Price, Revenue, Gross Margin and Market Share (2018-2023)
       2.6.5 LifeTech Recent Developments/Updates

3 Competitive Environment: PFO Closure Device by Manufacturer

   3.1 Global PFO Closure Device Sales Quantity by Manufacturer (2018-2023)
   3.2 Global PFO Closure Device Revenue by Manufacturer (2018-2023)
   3.3 Global PFO Closure Device Average Price by Manufacturer (2018-2023)
   3.4 Market Share Analysis (2022)
       3.4.1 Producer Shipments of PFO Closure Device by Manufacturer Revenue ($MM) and Market Share (%): 2022
       3.4.2 Top 3 PFO Closure Device Manufacturer Market Share in 2022
       3.4.2 Top 6 PFO Closure Device Manufacturer Market Share in 2022
   3.5 PFO Closure Device Market: Overall Company Footprint Analysis
       3.5.1 PFO Closure Device Market: Region Footprint
       3.5.2 PFO Closure Device Market: Company Product Type Footprint
       3.5.3 PFO Closure Device Market: Company Product Application Footprint
   3.6 New Market Entrants and Barriers to Market Entry
   3.7 Mergers, Acquisition, Agreements, and Collaborations

4 Consumption Analysis by Region

   4.1 Global PFO Closure Device Market Size by Region
       4.1.1 Global PFO Closure Device Sales Quantity by Region (2018-2029)
       4.1.2 Global PFO Closure Device Consumption Value by Region (2018-2029)
       4.1.3 Global PFO Closure Device Average Price by Region (2018-2029)
   4.2 North America PFO Closure Device Consumption Value (2018-2029)
   4.3 Europe PFO Closure Device Consumption Value (2018-2029)
   4.4 Asia-Pacific PFO Closure Device Consumption Value (2018-2029)
   4.5 South America PFO Closure Device Consumption Value (2018-2029)
   4.6 Middle East and Africa PFO Closure Device Consumption Value (2018-2029)

5 Market Segment by Type

   5.1 Global PFO Closure Device Sales Quantity by Type (2018-2029)
   5.2 Global PFO Closure Device Consumption Value by Type (2018-2029)
   5.3 Global PFO Closure Device Average Price by Type (2018-2029)

6 Market Segment by Application

   6.1 Global PFO Closure Device Sales Quantity by Application (2018-2029)
   6.2 Global PFO Closure Device Consumption Value by Application (2018-2029)
   6.3 Global PFO Closure Device Average Price by Application (2018-2029)

7 North America

   7.1 North America PFO Closure Device Sales Quantity by Type (2018-2029)
   7.2 North America PFO Closure Device Sales Quantity by Application (2018-2029)
   7.3 North America PFO Closure Device Market Size by Country
       7.3.1 North America PFO Closure Device Sales Quantity by Country (2018-2029)
       7.3.2 North America PFO Closure Device Consumption Value by Country (2018-2029)
       7.3.3 United States Market Size and Forecast (2018-2029)
       7.3.4 Canada Market Size and Forecast (2018-2029)
       7.3.5 Mexico Market Size and Forecast (2018-2029)

8 Europe

   8.1 Europe PFO Closure Device Sales Quantity by Type (2018-2029)
   8.2 Europe PFO Closure Device Sales Quantity by Application (2018-2029)
   8.3 Europe PFO Closure Device Market Size by Country
       8.3.1 Europe PFO Closure Device Sales Quantity by Country (2018-2029)
       8.3.2 Europe PFO Closure Device Consumption Value by Country (2018-2029)
       8.3.3 Germany Market Size and Forecast (2018-2029)
       8.3.4 France Market Size and Forecast (2018-2029)
       8.3.5 United Kingdom Market Size and Forecast (2018-2029)
       8.3.6 Russia Market Size and Forecast (2018-2029)
       8.3.7 Italy Market Size and Forecast (2018-2029)

9 Asia-Pacific

   9.1 Asia-Pacific PFO Closure Device Sales Quantity by Type (2018-2029)
   9.2 Asia-Pacific PFO Closure Device Sales Quantity by Application (2018-2029)
   9.3 Asia-Pacific PFO Closure Device Market Size by Region
       9.3.1 Asia-Pacific PFO Closure Device Sales Quantity by Region (2018-2029)
       9.3.2 Asia-Pacific PFO Closure Device Consumption Value by Region (2018-2029)
       9.3.3 China Market Size and Forecast (2018-2029)
       9.3.4 Japan Market Size and Forecast (2018-2029)
       9.3.5 Korea Market Size and Forecast (2018-2029)
       9.3.6 India Market Size and Forecast (2018-2029)
       9.3.7 Southeast Asia Market Size and Forecast (2018-2029)
       9.3.8 Australia Market Size and Forecast (2018-2029)

10 South America

   10.1 South America PFO Closure Device Sales Quantity by Type (2018-2029)
   10.2 South America PFO Closure Device Sales Quantity by Application (2018-2029)
   10.3 South America PFO Closure Device Market Size by Country
       10.3.1 South America PFO Closure Device Sales Quantity by Country (2018-2029)
       10.3.2 South America PFO Closure Device Consumption Value by Country (2018-2029)
       10.3.3 Brazil Market Size and Forecast (2018-2029)
       10.3.4 Argentina Market Size and Forecast (2018-2029)

11 Middle East & Africa

   11.1 Middle East & Africa PFO Closure Device Sales Quantity by Type (2018-2029)
   11.2 Middle East & Africa PFO Closure Device Sales Quantity by Application (2018-2029)
   11.3 Middle East & Africa PFO Closure Device Market Size by Country
       11.3.1 Middle East & Africa PFO Closure Device Sales Quantity by Country (2018-2029)
       11.3.2 Middle East & Africa PFO Closure Device Consumption Value by Country (2018-2029)
       11.3.3 Turkey Market Size and Forecast (2018-2029)
       11.3.4 Egypt Market Size and Forecast (2018-2029)
       11.3.5 Saudi Arabia Market Size and Forecast (2018-2029)
       11.3.6 South Africa Market Size and Forecast (2018-2029)

12 Market Dynamics

   12.1 PFO Closure Device Market Drivers
   12.2 PFO Closure Device Market Restraints
   12.3 PFO Closure Device Trends Analysis
   12.4 Porters Five Forces Analysis
       12.4.1 Threat of New Entrants
       12.4.2 Bargaining Power of Suppliers
       12.4.3 Bargaining Power of Buyers
       12.4.4 Threat of Substitutes
       12.4.5 Competitive Rivalry
   12.5 Influence of COVID-19 and Russia-Ukraine War
       12.5.1 Influence of COVID-19
       12.5.2 Influence of Russia-Ukraine War

13 Raw Material and Industry Chain

   13.1 Raw Material of PFO Closure Device and Key Manufacturers
   13.2 Manufacturing Costs Percentage of PFO Closure Device
   13.3 PFO Closure Device Production Process
   13.4 PFO Closure Device Industrial Chain

14 Shipments by Distribution Channel

   14.1 Sales Channel
       14.1.1 Direct to End-User
       14.1.2 Distributors
   14.2 PFO Closure Device Typical Distributors
   14.3 PFO Closure Device Typical Customers

15 Research Findings and Conclusion

16 Appendix

   16.1 Methodology
   16.2 Research Process and Data Source
   16.3 Disclaimer
 

List of Tables

   Table 1. Global PFO Closure Device Consumption Value by Type, (USD Million), 2018 & 2022 & 2029
   Table 2. Global PFO Closure Device Consumption Value by Application, (USD Million), 2018 & 2022 & 2029
   Table 3. Abbott Basic Information, Manufacturing Base and Competitors
   Table 4. Abbott Major Business
   Table 5. Abbott PFO Closure Device Product and Services
   Table 6. Abbott PFO Closure Device Sales Quantity (Units), Average Price (US$/Unit), Revenue (USD Million), Gross Margin and Market Share (2018-2023)
   Table 7. Abbott Recent Developments/Updates
   Table 8. Occlutech Basic Information, Manufacturing Base and Competitors
   Table 9. Occlutech Major Business
   Table 10. Occlutech PFO Closure Device Product and Services
   Table 11. Occlutech PFO Closure Device Sales Quantity (Units), Average Price (US$/Unit), Revenue (USD Million), Gross Margin and Market Share (2018-2023)
   Table 12. Occlutech Recent Developments/Updates
   Table 13. Starway Basic Information, Manufacturing Base and Competitors
   Table 14. Starway Major Business
   Table 15. Starway PFO Closure Device Product and Services
   Table 16. Starway PFO Closure Device Sales Quantity (Units), Average Price (US$/Unit), Revenue (USD Million), Gross Margin and Market Share (2018-2023)
   Table 17. Starway Recent Developments/Updates
   Table 18. W. L. Gore & Associates Basic Information, Manufacturing Base and Competitors
   Table 19. W. L. Gore & Associates Major Business
   Table 20. W. L. Gore & Associates PFO Closure Device Product and Services
   Table 21. W. L. Gore & Associates PFO Closure Device Sales Quantity (Units), Average Price (US$/Unit), Revenue (USD Million), Gross Margin and Market Share (2018-2023)
   Table 22. W. L. Gore & Associates Recent Developments/Updates
   Table 23. Cardia Basic Information, Manufacturing Base and Competitors
   Table 24. Cardia Major Business
   Table 25. Cardia PFO Closure Device Product and Services
   Table 26. Cardia PFO Closure Device Sales Quantity (Units), Average Price (US$/Unit), Revenue (USD Million), Gross Margin and Market Share (2018-2023)
   Table 27. Cardia Recent Developments/Updates
   Table 28. LifeTech Basic Information, Manufacturing Base and Competitors
   Table 29. LifeTech Major Business
   Table 30. LifeTech PFO Closure Device Product and Services
   Table 31. LifeTech PFO Closure Device Sales Quantity (Units), Average Price (US$/Unit), Revenue (USD Million), Gross Margin and Market Share (2018-2023)
   Table 32. LifeTech Recent Developments/Updates
   Table 33. Global PFO Closure Device Sales Quantity by Manufacturer (2018-2023) & (Units)
   Table 34. Global PFO Closure Device Revenue by Manufacturer (2018-2023) & (USD Million)
   Table 35. Global PFO Closure Device Average Price by Manufacturer (2018-2023) & (US$/Unit)
   Table 36. Market Position of Manufacturers in PFO Closure Device, (Tier 1, Tier 2, and Tier 3), Based on Consumption Value in 2022
   Table 37. Head Office and PFO Closure Device Production Site of Key Manufacturer
   Table 38. PFO Closure Device Market: Company Product Type Footprint
   Table 39. PFO Closure Device Market: Company Product Application Footprint
   Table 40. PFO Closure Device New Market Entrants and Barriers to Market Entry
   Table 41. PFO Closure Device Mergers, Acquisition, Agreements, and Collaborations
   Table 42. Global PFO Closure Device Sales Quantity by Region (2018-2023) & (Units)
   Table 43. Global PFO Closure Device Sales Quantity by Region (2024-2029) & (Units)
   Table 44. Global PFO Closure Device Consumption Value by Region (2018-2023) & (USD Million)
   Table 45. Global PFO Closure Device Consumption Value by Region (2024-2029) & (USD Million)
   Table 46. Global PFO Closure Device Average Price by Region (2018-2023) & (US$/Unit)
   Table 47. Global PFO Closure Device Average Price by Region (2024-2029) & (US$/Unit)
   Table 48. Global PFO Closure Device Sales Quantity by Type (2018-2023) & (Units)
   Table 49. Global PFO Closure Device Sales Quantity by Type (2024-2029) & (Units)
   Table 50. Global PFO Closure Device Consumption Value by Type (2018-2023) & (USD Million)
   Table 51. Global PFO Closure Device Consumption Value by Type (2024-2029) & (USD Million)
   Table 52. Global PFO Closure Device Average Price by Type (2018-2023) & (US$/Unit)
   Table 53. Global PFO Closure Device Average Price by Type (2024-2029) & (US$/Unit)
   Table 54. Global PFO Closure Device Sales Quantity by Application (2018-2023) & (Units)
   Table 55. Global PFO Closure Device Sales Quantity by Application (2024-2029) & (Units)
   Table 56. Global PFO Closure Device Consumption Value by Application (2018-2023) & (USD Million)
   Table 57. Global PFO Closure Device Consumption Value by Application (2024-2029) & (USD Million)
   Table 58. Global PFO Closure Device Average Price by Application (2018-2023) & (US$/Unit)
   Table 59. Global PFO Closure Device Average Price by Application (2024-2029) & (US$/Unit)
   Table 60. North America PFO Closure Device Sales Quantity by Type (2018-2023) & (Units)
   Table 61. North America PFO Closure Device Sales Quantity by Type (2024-2029) & (Units)
   Table 62. North America PFO Closure Device Sales Quantity by Application (2018-2023) & (Units)
   Table 63. North America PFO Closure Device Sales Quantity by Application (2024-2029) & (Units)
   Table 64. North America PFO Closure Device Sales Quantity by Country (2018-2023) & (Units)
   Table 65. North America PFO Closure Device Sales Quantity by Country (2024-2029) & (Units)
   Table 66. North America PFO Closure Device Consumption Value by Country (2018-2023) & (USD Million)
   Table 67. North America PFO Closure Device Consumption Value by Country (2024-2029) & (USD Million)
   Table 68. Europe PFO Closure Device Sales Quantity by Type (2018-2023) & (Units)
   Table 69. Europe PFO Closure Device Sales Quantity by Type (2024-2029) & (Units)
   Table 70. Europe PFO Closure Device Sales Quantity by Application (2018-2023) & (Units)
   Table 71. Europe PFO Closure Device Sales Quantity by Application (2024-2029) & (Units)
   Table 72. Europe PFO Closure Device Sales Quantity by Country (2018-2023) & (Units)
   Table 73. Europe PFO Closure Device Sales Quantity by Country (2024-2029) & (Units)
   Table 74. Europe PFO Closure Device Consumption Value by Country (2018-2023) & (USD Million)
   Table 75. Europe PFO Closure Device Consumption Value by Country (2024-2029) & (USD Million)
   Table 76. Asia-Pacific PFO Closure Device Sales Quantity by Type (2018-2023) & (Units)
   Table 77. Asia-Pacific PFO Closure Device Sales Quantity by Type (2024-2029) & (Units)
   Table 78. Asia-Pacific PFO Closure Device Sales Quantity by Application (2018-2023) & (Units)
   Table 79. Asia-Pacific PFO Closure Device Sales Quantity by Application (2024-2029) & (Units)
   Table 80. Asia-Pacific PFO Closure Device Sales Quantity by Region (2018-2023) & (Units)
   Table 81. Asia-Pacific PFO Closure Device Sales Quantity by Region (2024-2029) & (Units)
   Table 82. Asia-Pacific PFO Closure Device Consumption Value by Region (2018-2023) & (USD Million)
   Table 83. Asia-Pacific PFO Closure Device Consumption Value by Region (2024-2029) & (USD Million)
   Table 84. South America PFO Closure Device Sales Quantity by Type (2018-2023) & (Units)
   Table 85. South America PFO Closure Device Sales Quantity by Type (2024-2029) & (Units)
   Table 86. South America PFO Closure Device Sales Quantity by Application (2018-2023) & (Units)
   Table 87. South America PFO Closure Device Sales Quantity by Application (2024-2029) & (Units)
   Table 88. South America PFO Closure Device Sales Quantity by Country (2018-2023) & (Units)
   Table 89. South America PFO Closure Device Sales Quantity by Country (2024-2029) & (Units)
   Table 90. South America PFO Closure Device Consumption Value by Country (2018-2023) & (USD Million)
   Table 91. South America PFO Closure Device Consumption Value by Country (2024-2029) & (USD Million)
   Table 92. Middle East & Africa PFO Closure Device Sales Quantity by Type (2018-2023) & (Units)
   Table 93. Middle East & Africa PFO Closure Device Sales Quantity by Type (2024-2029) & (Units)
   Table 94. Middle East & Africa PFO Closure Device Sales Quantity by Application (2018-2023) & (Units)
   Table 95. Middle East & Africa PFO Closure Device Sales Quantity by Application (2024-2029) & (Units)
   Table 96. Middle East & Africa PFO Closure Device Sales Quantity by Region (2018-2023) & (Units)
   Table 97. Middle East & Africa PFO Closure Device Sales Quantity by Region (2024-2029) & (Units)
   Table 98. Middle East & Africa PFO Closure Device Consumption Value by Region (2018-2023) & (USD Million)
   Table 99. Middle East & Africa PFO Closure Device Consumption Value by Region (2024-2029) & (USD Million)
   Table 100. PFO Closure Device Raw Material
   Table 101. Key Manufacturers of PFO Closure Device Raw Materials
   Table 102. PFO Closure Device Typical Distributors
   Table 103. PFO Closure Device Typical Customers

List of Figures

   Figure 1. PFO Closure Device Picture
   Figure 2. Global PFO Closure Device Consumption Value by Type, (USD Million), 2018 & 2022 & 2029
   Figure 3. Global PFO Closure Device Consumption Value Market Share by Type in 2022
   Figure 4. Non-degradable Examples
   Figure 5. Degradable Examples
   Figure 6. Global PFO Closure Device Consumption Value by Application, (USD Million), 2018 & 2022 & 2029
   Figure 7. Global PFO Closure Device Consumption Value Market Share by Application in 2022
   Figure 8. Public Hospital Examples
   Figure 9. Private Hospital Examples
   Figure 10. Global PFO Closure Device Consumption Value, (USD Million): 2018 & 2022 & 2029
   Figure 11. Global PFO Closure Device Consumption Value and Forecast (2018-2029) & (USD Million)
   Figure 12. Global PFO Closure Device Sales Quantity (2018-2029) & (Units)
   Figure 13. Global PFO Closure Device Average Price (2018-2029) & (US$/Unit)
   Figure 14. Global PFO Closure Device Sales Quantity Market Share by Manufacturer in 2022
   Figure 15. Global PFO Closure Device Consumption Value Market Share by Manufacturer in 2022
   Figure 16. Producer Shipments of PFO Closure Device by Manufacturer Sales Quantity ($MM) and Market Share (%): 2021
   Figure 17. Top 3 PFO Closure Device Manufacturer (Consumption Value) Market Share in 2022
   Figure 18. Top 6 PFO Closure Device Manufacturer (Consumption Value) Market Share in 2022
   Figure 19. Global PFO Closure Device Sales Quantity Market Share by Region (2018-2029)
   Figure 20. Global PFO Closure Device Consumption Value Market Share by Region (2018-2029)
   Figure 21. North America PFO Closure Device Consumption Value (2018-2029) & (USD Million)
   Figure 22. Europe PFO Closure Device Consumption Value (2018-2029) & (USD Million)
   Figure 23. Asia-Pacific PFO Closure Device Consumption Value (2018-2029) & (USD Million)
   Figure 24. South America PFO Closure Device Consumption Value (2018-2029) & (USD Million)
   Figure 25. Middle East & Africa PFO Closure Device Consumption Value (2018-2029) & (USD Million)
   Figure 26. Global PFO Closure Device Sales Quantity Market Share by Type (2018-2029)
   Figure 27. Global PFO Closure Device Consumption Value Market Share by Type (2018-2029)
   Figure 28. Global PFO Closure Device Average Price by Type (2018-2029) & (US$/Unit)
   Figure 29. Global PFO Closure Device Sales Quantity Market Share by Application (2018-2029)
   Figure 30. Global PFO Closure Device Consumption Value Market Share by Application (2018-2029)
   Figure 31. Global PFO Closure Device Average Price by Application (2018-2029) & (US$/Unit)
   Figure 32. North America PFO Closure Device Sales Quantity Market Share by Type (2018-2029)
   Figure 33. North America PFO Closure Device Sales Quantity Market Share by Application (2018-2029)
   Figure 34. North America PFO Closure Device Sales Quantity Market Share by Country (2018-2029)
   Figure 35. North America PFO Closure Device Consumption Value Market Share by Country (2018-2029)
   Figure 36. United States PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 37. Canada PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 38. Mexico PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 39. Europe PFO Closure Device Sales Quantity Market Share by Type (2018-2029)
   Figure 40. Europe PFO Closure Device Sales Quantity Market Share by Application (2018-2029)
   Figure 41. Europe PFO Closure Device Sales Quantity Market Share by Country (2018-2029)
   Figure 42. Europe PFO Closure Device Consumption Value Market Share by Country (2018-2029)
   Figure 43. Germany PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 44. France PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 45. United Kingdom PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 46. Russia PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 47. Italy PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 48. Asia-Pacific PFO Closure Device Sales Quantity Market Share by Type (2018-2029)
   Figure 49. Asia-Pacific PFO Closure Device Sales Quantity Market Share by Application (2018-2029)
   Figure 50. Asia-Pacific PFO Closure Device Sales Quantity Market Share by Region (2018-2029)
   Figure 51. Asia-Pacific PFO Closure Device Consumption Value Market Share by Region (2018-2029)
   Figure 52. China PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 53. Japan PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 54. Korea PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 55. India PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 56. Southeast Asia PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 57. Australia PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 58. South America PFO Closure Device Sales Quantity Market Share by Type (2018-2029)
   Figure 59. South America PFO Closure Device Sales Quantity Market Share by Application (2018-2029)
   Figure 60. South America PFO Closure Device Sales Quantity Market Share by Country (2018-2029)
   Figure 61. South America PFO Closure Device Consumption Value Market Share by Country (2018-2029)
   Figure 62. Brazil PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 63. Argentina PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 64. Middle East & Africa PFO Closure Device Sales Quantity Market Share by Type (2018-2029)
   Figure 65. Middle East & Africa PFO Closure Device Sales Quantity Market Share by Application (2018-2029)
   Figure 66. Middle East & Africa PFO Closure Device Sales Quantity Market Share by Region (2018-2029)
   Figure 67. Middle East & Africa PFO Closure Device Consumption Value Market Share by Region (2018-2029)
   Figure 68. Turkey PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 69. Egypt PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 70. Saudi Arabia PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 71. South Africa PFO Closure Device Consumption Value and Growth Rate (2018-2029) & (USD Million)
   Figure 72. PFO Closure Device Market Drivers
   Figure 73. PFO Closure Device Market Restraints
   Figure 74. PFO Closure Device Market Trends
   Figure 75. Porters Five Forces Analysis
   Figure 76. Manufacturing Cost Structure Analysis of PFO Closure Device in 2022
   Figure 77. Manufacturing Process Analysis of PFO Closure Device
   Figure 78. PFO Closure Device Industrial Chain
   Figure 79. Sales Quantity Channel: Direct to End-User vs Distributors
   Figure 80. Direct Channel Pros & Cons
   Figure 81. Indirect Channel Pros & Cons
   Figure 82. Methodology
   Figure 83. Research Process and Data Source